Small business owner Paul Hague has threatened to leave Bognor Regis if his local post office closes.
Mr Hague has been based in Station Road for the past year, supplying accessories to IVF laboratories around the country.
He chose his premises because they are two doors away from the nearest post office.
But the Station Road branch is among
five earmarked by Post Office Ltd for closure in May.
Mr Hague said the inconvenience of having to walk through the town centre to the main post office in the High Street and wait in its queues meant he would be unable to carry on in the town.
He told a public meeting held to protest about the proposed closures he had posted four parcels at the branch for special delivery that day.
"If that branch in Station Road closes, there's no point in my continuing in business in Bognor.
"I will be forced to move out of the area. There's no other possibility," he said.
The Walberton resident added that if he left, his spending around the town centre on supplies for his business would also go.
He believed his decision could well be followed by other firms who rent neighbouring offices in the same building.
Fellow business owner Ralph Page, who sends out religious tapes and CDs, said he would be similarly hit if the Station Road branch shut.
"It's a ten-minute trip every day to that branch from my offices on the corner of Crescent Road and Queensway," he said.
"That is going to be an hour at least if I have to go to the main post office.
"I've always seen a queue whenever I have been in there and that is going to develop more and more if these closures go ahead."
Linden Road resident Sheila Gibbons added to the warnings about the impact of the closure of the branch in Station Road.
"It's going to take an hour to be served in the main post office," she complained.
"There are going to be queues out onto the street.
"There are already queues from the sorting office on the left and queues from the post office counters on the left."
Staff from the Station Road branch were among the 100 or so people at the meeting.
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